| Characteristic | Details |
|---|---|
| Generic Name | Prednisolone |
| Class | Glucocorticoid |
| Available Dosages | 5 mg, 10 mg, 20 mg, 40 mg |
| Route of Administration | Oral |
| Common Brand Names | Millipred, Orapred |
| Discover More About Prednisolone | |
Pharmacokinetics
Prednisolone 20 mg is a synthetic glucocorticoid. It mimics cortisol effects in the body. Administered orally, its absorption is swift and complete. Plasma concentrations peak within 1-2 hours post-ingestion. The drug’s biological half-life ranges from 2 to 4 hours. It undergoes extensive hepatic metabolism.
The drug displays a high volume of distribution, indicating significant tissue penetration. Protein binding in plasma remains at approximately 90%. Renal excretion is predominant, with metabolites appearing in urine. Bioavailability is not significantly affected by food intake. Prednisolone’s pharmacokinetic profile supports its widespread therapeutic use.
Other Uses for Prednisolone
Apart from conventional applications, prednisolone 10 mg serves various therapeutic roles. In ophthalmology, it reduces inflammation post-eye surgery. It alleviates symptoms of acute respiratory distress syndrome. Prednisolone finds utility in treating severe skin conditions like eczema and psoriasis.
It acts as an immunosuppressant in organ transplant patients. Veterinary medicine also employs prednisolone for treating canine inflammatory conditions. This glucocorticoid continues to expand its clinical significance. Each application underscores its potent anti-inflammatory and immunomodulatory properties.
FDA-Approved Indications
Prednisolone’s FDA endorsements include multiple inflammatory and autoimmune disorders. Its efficacy in managing arthritis, ulcerative colitis, and lupus is well-documented. Prednisolone 5 mg reduces inflammation and immune response in these conditions.
The drug also treats allergic reactions and hematological disorders. Its approval for respiratory illnesses like asthma highlights its therapeutic versatility. Prednisolone remains a cornerstone in managing chronic and acute inflammatory states.
Prednisolone Interactions
Prednisolone’s efficacy can be altered by interactions with other substances. Concomitant use with NSAIDs increases gastrointestinal bleeding risk. Anticoagulants may experience reduced efficacy when paired with prednisolone.
Patients taking certain antiepileptics could encounter altered plasma levels. Antifungal agents like ketoconazole may heighten prednisolone concentrations. Healthcare providers should evaluate potential interactions prior to initiating therapy.
How to Cope with Side Effects of Prednisolone
Side effects of prednisolone 40 mg can be managed with specific strategies. Common issues include weight gain, mood swings, and increased blood pressure. Patients should monitor diet and exercise to counteract weight changes. Consulting healthcare providers about psychological symptoms is advisable.
Adequate hydration and salt reduction can mitigate hypertension. Bone density might decrease; supplements may be recommended. Effective management of side effects ensures continued therapeutic benefits of prednisolone.
Where to Buy Prednisolone Online
Online pharmacies offer a convenient route to purchase prednisolone. Verifying the legitimacy of the pharmacy is crucial. Look for pharmacies with certification from the National Association of Boards of Pharmacy.
Price comparison across platforms can ensure cost-effective purchasing. Some sites may offer patient assistance programs for affordability. Always consult a healthcare provider before initiating online purchases of prednisolone.
| Aspect | Details |
|---|---|
| Storage | Room Temperature |
| Shelf Life | 3 Years |
Data origin:
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